1803 The Newark Female Charitable Society is organized.

1804 Sacagawea begins serving as a guide for the Lewis and Clark expedition.

1813 Pennsylvania v. Addicks introduces the concept of "the best interests of the child" in custody cases.

1819 Rebecca Gratz helps establish the Female Hebrew Benevolent Society.

1821 Emma Hart Willard founds the Troy Female Seminary in New York.

1824 Adams Female Academy opens in Londonderry, New Hampshire under the leadership of Zilpah Polly Grant.

1829 Perkins School for the Blind Incorporated

1830 The Indian Removal Act is signed into law.

1832 Boston Female Anti-Slavery Society is founded.

1833 Oberlin College becomes the first coeducational collegiate institution in the United States.

1835 Advertisement for the capture of Harriet Jacobs.

1836 Angelina Grimke's Appeal to the Christian Women of the South

1837 Laura Bridgman becomes a student at the Perkins School for the Blind.

1837 Hannah Valentine and Lethe Jackson Slave Letters, 1837-1838

1838 Angelina Grimke addresses Legislature

1840 Lowell Offering See Magazines section of Harvard Library's Women Working, 1800-1930. Lucretia Mott is denied a seat at the World Anti- Slavery Conference in London because of her gender.

1841 Dorothea Dix Begins Her Crusade, March 28, 1841

1847 Lucy Stone graduates from Oberlin College. Stone refuses to write a commencement address because she would not be allowed to read it herself.

1848 Ellen Craft escapes slavery by posing as a white man.

1849 Elizabeth Blackwell becomes the first woman to receive the M.D. degree.

1850 The Female Medical College of Pennsylvania opens.

1850 Harriet Tubman makes her first trip to the South as a conductor on the Underground Railroad.

1852 Elizabeth Cady Stanton and Susan B. Anthony become active in the Women's New York State Temperance Society.

1853 Harriet Beecher Stowe's Uncle Tom's Cablin is published.

1861 Harriet Jacobs' Incidents in the Life of a Slave Girl is published.

1864 Sand Creek Massacre leaves at least 150 Cheyennes and Arapahos dead.

1869 Elizabeth Cady Stanton and Susan B. Anthony found the National Woman Suffrage Association (NWSA), and Lucy Stone helps found the more moderate American Woman Suffrage Association.

1870 Sophia Smith Endows New Women's College, March 8, 1870

1873 Comstock Law prohibits the distribution of information or devices relating to abortion or birth control.

1873 Ellen Swallow Richards becomes the first woman graduate of MIT.

1874 The Woman's Christian Temperance Union is founded.

1876 Lydia E. Pinkham registers the label and trademark for Lydia E. Pinkham's Vegetable Compound.

1879 Belva Lockwood becomes the first woman admitted to the Supreme Court bar.

1879 Frances Willard is elected president of the National Women's Temperance Union.

1879  Mary Baker Eddy founds the First Church of Christ Scientist.

1881 Atlanta Baptist Female Seminary is founded by Sophia B. Packard and Harriet E. Giles.

1881 Clara Barton founds the American Red Cross.

1882 Association of Collegiate Alumnae, forerunner of the American Association of University Women, is formally organized.

1883 Sarah Winnemucca's Life Among the Piutes: Their Wrongs and Claims is the first book written by a Native American woman.

1884 M. Carey Thomas becomes Dean of Bryn Mawr College.

1885 Sharpshooter Annie Oakley begins touring with "Buffalo Bill" Cody's Wild West Show.

1887  Susanna Salter is elected mayor of Argonia, Kansas, thus becoming the first woman mayor in the country.

1889 Jane Addams and Ellen Gates Starr found Hull House in Chicago.

1889 Susan La Flesche Picotte becomes the first Native American woman medical doctor.

1890 General Federation of Women's Clubs is organized by Jane Croly.

1890 National American Woman Suffrage Association is formed.

1891 Lili'uokalani becomes queen of Hawaii.

1892 Ellis Island opens on January 1. Fifteen year old Annie Moore is the first immigrant to pass through Ellis Island.

1892 General Federation of Women's Clubs is founded.

1892 Mary Elizabeth Garrett's gift of $306,977 enables the medical school of Johns Hopkins University to open the following year.

1893 World's Columbian Exposition in Chicago Working Women

1895 Draft of Elizabeth Cady Stanton's The Woman's Bible

1896 Fannie Farmer's Boston Cooking-School Cookbook is published.

1896 Massachusetts Foundation for the Humanities] Plessy v. Ferguson ruling allows "equal but separate accommodations for the white and colored races."

1898 Charlotte Perkins Gilman's Women and Economics is published.

1899 Carrie Nation begins her militant crusade against saloons.

1899 Florence Kelley becomes head of the National Consumer's League.